Los Angeles Healthcare System Study Links Fluoride With #1 Cause Of Death – Cardiovascular Disease

Source: Durham Against Fluoride

ORIGINAL ARTICLE: Association of vascular fluoride uptake with vascular calcification and Coronary Artery Disease

A January 2012 study published by the VA Greater Los Angeles Healthcare System has linked Sodium Fluoride uptake with the hardening & calcification of major arteries, also known as Cardiovascular disease & the number one cause of death in the United States.

The study first appeared in the Nuclear Medicine Communications Journal, a “rapid communications journal publishing research and clinical work in all areas of nuclear medicine for an international readership,” but these observations have not yet been picked up by the collective. The research was performed by nuclear medicine physicians who retrospectively reviewed the imaging data and cardiovascular history of 61 patients who received whole-body sodium [F]fluoride PET/CT studies at their institution from 2009 to 2010. Fluoride uptake and calcification in major arteries, including coronary arteries, were analyzed by both visual assessment and standardized uptake value measurement.

In the introduction section it is interestingly noted that the phenomenon of hardening arteries & what risks that may pose to our health has been extensively studied, however Fluoride uptake & it’s clinical significance to coronary arteries has not yet been documented:

To predict and prevent any deadly cardiovascular events, extensive studies have been conducted to evaluate the risk of cardiovascular disease. Over the past decade, many cardiovascular studies focused on the calcification process in atherosclerosis (hardening of arteries). Calcification in atherosclerosis occurs through an active process that resembles bone formation and is controlled by complex enzymatic and cellular pathways. Coronary artery calcification parallels atherosclerosis progress and is strongly and linearly correlated with fluorodeoxyglucose uptake in coronary arteries. However, the clinical significance of fluoride uptake in coronoary arteries has not been documented.

The results of this study therefore have vast implications for our collectively becoming aware of one main contributing factor to the ongoing scourge heart disease, namely municipal water fluoridation. This is especially true in consideration that 80% of Americans are since 1957 forcibly fluoridated via their public drinking water & cardiovascular disease still remains the #1 cause of death in America (600,000/year).

Despite this study’s relative significance to the research produced by Harvard which concluded higher Fluoride uptake predictably lowers the Intelligence Quotient in humans, these specific conclusions have unfortunately not made it into mainstream news to the same degree. Although the full article admits more research should be conducted on the clinical significance of Fluoride uptake, this is the exact problem we face (lack of studies) nearly 60 years into the forced, highly systematic & ubiquitous fluoridation of our municipal water supplies! One wonders the true extent of damage done if our scientists are only just now realizing the tragic link between Fluoride uptake & a disease that kills more Americans than one hundred and seventy 9/11s combined EACH YEAR.

This blows a huge hole in the already horrendously flawed pro-fluoride argument which posits that drinking Fluoride only affects the teeth and does not have any health hazards to other organs of the body. For fluoride fighters in the area, listen to me debunk local Public Health Terrorist Rebecca King once more, who ridiculously claims ingestion of fluoride is the best thing since sliced bread as it returns to the mouth in our saliva & continuously bathes our teeth in Fluoride-rich fluid! Such a bold faced & twisted manipulation of the facts is incredible in that it intrinsically admits Fluoride is penetrating all cells of the body- even the salivation glands.

So What were the results?

Patients

There were 58 male patients and three female patients. Detailed clinical histories and the presence of cardiovascular risk factors, such as hypertension, diabetes, hypercholesterolemia, smoking history, obesity, and history of cardiovascular events, were obtained for all patients. The clinical characteristics of the patients are summarized in Table 1.

Table 1 Patients' Clinical CharacteristicsImaging and Statistical Analyses

sd_CTorthopedics_main_enCT and PET images were coregistered by the Philips Extended Brilliance workstation (Philips Healthcare). CT, PET, and fused PET/CT images were evaluated visually and semi-quantitatively simultaneously using the same workstation. All images were analyzed by two independent nuclear medicine physicians blinded to all patients’ clinical information. Inter-reader reproducibility was excellent and was evaluated using an intraclass correlation coefficient (0.89). Vascular calcification was identified as positive on CT images if the target was visually detectable with a greater than 130 Hounsfield units. CT-attenuated PET images were evaluated for fluoride uptake in major arteries. Background activity was based on the standardized uptake value (SUV) of the blood pool, which was calculated from the mean SUVs of three circular regions of interest (ROIs) placed in the left atrium, mid lumen of the aortic arch, and abdominal aorta at the level of the celiac trunk on axial images. The sizes of ROIs were 2cm in diameter for the left atrium and 1cm for the aortic arch and the abdominal aorta.

Results (Abbreviated, click link to view original article)

Patients’ age and reasons for sodium fluoride PET/CT imaging are summarized in Table 1. Most patients were men with a median age of 66 years (27-91 years). The majority of patients (69%) had more than one risk factor for coronary artery disease.

Arterial sodium Fluoride uptake and calcification

Arterial wall sodium fluoride uptake and calcification were evaluated in major arteries, including carotid arteries, the thoracic ascending (including aortic arch) aorta, the thoracic descending aorta, the abdominal aorta, femoral arteries, and major branches of coronary arteries. Iliac arteries were not evaluated because of frequently observed urinary and occasional bowel uptake in the pelvis, which interferes with the accurate assessment of iliac vessels. For coronary arteries, four major branches were evaluated. An example of fluoride uptake in femoral arteries is shown in Fig. 1. Orthogonal views of fluoride uptake in the aorta and coronary arteries are shown in Figs 2 and 3.
Figure1
Figure 2Figure3Relationship between coronary fluoride uptake and cardiovascular risk factorsThe coronary arteries were also investigated for fluoride uptake. Four major branches of coronary arteries, including left main artery (LMA), left anterior descending (LAD), left circumflex (LCA), and right coronary arteriy (RCA) were evaluated. Fluoride uptake was more frequently observed in the LAD and LCAs. A similar pattern was also identified in coronary artery calcification. In each individual coronary branch, calcification was more frequently observed than fluoride uptake (Table 2). Table2
  • Among 10 patients who had significant three-vessel coronary calcifications, 80% demonstrated fluoride uptake in at least one coronary branch (data not shown).
  • Cardiovascular risk factors including hypertension, obesity, diabetes, hypercholesterolemia, smoking history, and history of coronary artery disease were reviewed in all patients (Table 3).
  • The majority of the patients (69%) had more than one cardiovascular risk factor; however, neither the individual cardiovascular risk factor nor the number of risk factors was significantly correlated with coronary fluoride uptake (Table 3).
Table3
Nine patients had a history of cardiovascular events. Among them, eight demonstrated identifiable coronary fluoride uptake. There was significant correlation between coronary calcification and fluoride uptake in this group evaluated by Fisher’s exact test (Table 3). All nine patients also demonstrated coronary calcification on CT images. We also compared the SUVmax in coronary arteries between patients with and without a history of cardiovascular events. The average coronary SUV max in patients with a history of cardiovascular events was 1.70, significantly higher than 1.39 for patients without a history of cardiovascular events (P=0.029, two-tailed Student’s t-test). No correlation was observed between cardiovascular risk factors and fluoride uptake in other vascular territories (noncoronary).

Discussion Highlights

Vascular calcification, in particular coronary calcification, has been shown to predict vascular events [25–27].

In our study, fluoride uptake and CT calcification are significantly correlated in the same arterial territories, except in the abdominal aorta. This is because of the extremely high positive rate (97%, only one patient demonstrated negative uptake) for fluoride uptake in the abdominal aorta.

Fluoride uptake either overlaps with calcification or locates adjacent to the detectable calcium deposits, suggesting that fluoride uptake and detectable calcification represent different stages of the atherosclerotic process.

We found that fluoride uptake in coronary arteries is significantly correlated with a patient’s history of cardiovascular events, and the uptake value in patients with cardiovascular events was significantly higher than that in patients without cardiovascular events. These results further support the fact that higher fluoride uptake in coronary arteries indicates increased cardiovascular risk.

The combination of sodium [18F]fluoride PET and CT is a promising imaging modality that provides both metabolic and anatomic information in evaluating vascular calcification. However, large-scale studies are needed to evaluate the clinical significance of fluoride PET/CT for imaging atherosclerosis.

Conclusion

Our study demonstrates that vascular calcification and fluoride uptake are significantly correlated in the same arterial territory, although not necessarily overlapping in the same anatomic locations. An increased fluoride uptake in coronary arteries may be associated with an increased cardiovascular risk. Combined anatomic and metabolic imaging with sodium [18F]fluoride PET/CT offers a promising, noninvasive method to evaluate atherosclerosis.

Russia’s small-scale organic agriculture model may hold the key to feeding the world

 

Source: Trueactivist.com

Imagine living in a country where having the freedom to cultivate your own land, tax-free and without government interference, is not only common but also encouraged for the purpose of promoting individual sovereignty and strong, healthy communities. Now imagine that in this same country, nearly all of your neighbors also cultivate their own land as part of a vast network of decentralized, self-sustaining, independent “eco-villages” that produce more than enough food to feed the entire country.

You might be thinking this sounds like some kind of utopian interpretation of historical America, but the country actually being described here is modern-day Russia. It turns out that Russia’s current agricultural model is one that thrives as a result of the millions of small-scale, family-owned and -operated, organically-cultivated farms that together produce the vast majority of the food consumed throughout the country.

Do Russians have more food freedom, independence than Americans?

A far cry from the unsustainable, chemical-dependent, industrialized agriculture system that dominates the American landscape today, Russia’s agricultural system, which is not technically a system at all, is run by the people and for the people. Thanks to government policies there that actually encourage autonomous family farming, rather than cater to the greed of chemical and biotechnology companies like they do here in the states, the vast majority of Russians are able and willing to grow their own food on privately-owned family plots known as “dachas.”

According to The Bovine, Russia’s Private Garden Plot Act, which was signed into law back in 2003, entitles every Russian citizen to a private plot of land, free of charge, ranging in size from 2.2 acres to 6.8 acres. Each plot can be used for growing food, or for simply vacationing or relaxing, and the government has agreed not to tax this land. And the result of this effort has been phenomenal, as Russian families collectively grow practically all the food they need.

“Essentially, what Russian gardeners do is demonstrate that gardeners can feed the world — and you do not need any GMOs, industrial farms, or any other technological gimmicks to guarantee everybody’s got enough food to eat,” writes Leonid Sharashkin, editor of the English version of the The Ringing Cedars series, a book collection that explains the history behind this effort to reconnect people with the earth and nature. (http://www.ringingcedars.com/)

Most food in Russia comes from backyard gardens

Back in 1999, it was estimated that 35 million small family plots throughout Russia, operated by 105 million people, or 71 percent of the Russian population, were producing about 50 percent of the nation’s milk supply, 60 percent of its meat supply, 87 percent of its berry and fruit supply, 77 percent of its vegetable supply, and an astounding 92 percent of its potato supply. The average Russian citizen, in other words, is fully empowered under this model to grow his own food, and meet the needs of his family and local community.

“Bear in mind that Russia only has 110 days of growing season per year — so in the U.S., for example, gardeners’ output could be substantially greater. Today; however, the area taken up by lawns in the U.S. is two times greater than that of Russia’s gardens — and it produces nothing but a multi-billion-dollar lawn care industry.”

The backyard gardening model is so effective throughout Russia that total output represents more than 50 percent of the nation’s entire agricultural output. Based on 2004 figures, the collective value of all the backyard produce grown in Russia is $14 billion, or 2.3 percent of Russia’s gross domestic product (GDP) – and this number only continues to increase as more and more Russians join the eco-village movement.

Sources for this article include:

http://thebovine.wordpress.com

http://www.proliberty.com/observer/20080211.htm

Obama’s Victory Is Very Bullish For This Google Search Query

Source: ZeroHedge

“Renounce Citizenship”

Simon Black’s always interesting insights on this ‘event’ can be found here.

Perhaps the geographical dispersion of those searches will be insightful, if rather paradoxical…

And by targeted MSA:

TSA forces dying leukemia patient to take off bandages

Source: Russia Today

A 34-year-old woman with terminal leukemia went through the Seattle-Tacoma Airport recently to take the last trip of her life — a vacation to Hawaii. She says she was traumatized, however, after the TSA humiliated her at a security check-point.

Michelle Dunaj of Roseville, Michigan eventually made her way to Hawaii after leaving the Washington State airport on October 2, but not without incident. She says that Transportation Security Administration agents were far from understanding and made her uncomfortable as she attempted to catch her departing flight. Dunaj tells reporters that officers with the TSA told her she couldn’t have a private pat-down and instead made her remove her bandages and even ruined a bag of saline solution she was carrying with her, all within plain sight of every other treveler passing through the security station.

“My issue is: It was in front of everyone, and everyone was looking at me like I was a criminal or like I was doing something wrong,” Dunaj tells The Associated Press this week. “It shouldn’t have been in front of everyone.”

Dunaj said she went out of her way to call the airline ahead of time, asked for a wheelchair and even took extra precautions to make sure she had the proper documentation for her feeding tubes and prescription medicine she was bringing with her. All of those attempts at easing the security screenings that have been condemned as over-evasive by its critics couldn’t make things easier, however, and now even the TSA says they stand by their actions.

Despite claims from the woman that one of her five bags of saline solution was tore open by an agent and that her requests to be screened at a separate facility were ignored, the TSA says its officers acted according to protocol. Even after her ordeal was over, she says she was told to “move along,” which she says she found “a little rude.”

“At no point did a TSA officer open the passenger’s medically necessary liquids and the passenger was never asked to remove or pull off any bandages,” the agency claims in a response issued this week, adding, “at any point, any passenger can request private screening with a witness present.”

“We have determined that our screening procedures were followed,” TSA Northwest Region spokeswoman Lorie Dankers adds to the Associated Press. “We work to make our screening procedures as minimally invasive as possible while providing the level of security that the American people want and deserve.”

Dunaj is expected to enter hospice on October 17, but says she managed to cross “number one” off her bucket list with her recent trip.

“Hawaii was one of the most beautiful things I’ve ever seen,” she tells the AP.

Earlier this month, The Star-Ledger newspaper out of New Jersey published the findings of an undercover, internal TSA investigation from earlier this year that found TSA agents at Newark Liberty International Airport, one of the busiest travel hubs in the country, were caught performing their security duties correctly just 16.7 percent of the time.